Verapamil

Information About Verapamil

Uses of Verapamil

Verapamil is commonly used to treat angina heart related chest pain and arrhythmias

How Verapamil Works

Verapamil is a calcium-channel blocker which acts by inhibiting the L-type calcium channels in the heart. It relaxes the heart and vascular smooth muscles and slows the automaticity of heart nodal conduction

Side Effects of Verapamil

Heart block, Bradycardia, Worsening of heart failure, Hypotension, Dizziness, Flushing, Peripheral oedema, Constipation, Liver dysfunction, Dyspnoea

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Verapamil Related Warnings

Alcohol Not Advisable

Verapamil is proved to increase the alcohol level in the blood and delay its elimination from the body. Thus, it is not advisable to take Verapamil and alcohol simultaneously as it can accentuate the effects of alcohol.

Pregnancy Not Safe

Although animal studies have shown no reproductive toxicity, Verapamil should not be used during pregnancy as it might cause relaxation of the uterus which may compromise the mother at term. Please consult your doctor.

Lactation Not Advisable

Verapamil is known to be secreted in human milk. Thus, Verapamil is not advisable to be used during breastfeeding. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Verapamil may cause side effects such as drowsiness at the initial treatment which could affect your ability to concentrate and drive.

Kidney Use With Care

Caution use has to be exercised in patients with renal impairments as the disposition has not been fully established in this group of patients.

Liver Use With Care

Dose adjustment is needed in patients with liver impairment.