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Zonisamide is commonly used to treat epilepsy
Zonisamide is a sulfonamide. It is hypothesized to block sodium and voltage-sensitive calcium channels which will then prevent neuronal depolarization.
Abdominal pain, Altered bowel habit, Dry mouth, Taste disturbance, Headache, Dizziness, Rash, Neurological disturbance
It is unsafe to consume alcohol with Zonisamide. Taking Zonisamide with alcohol may have additive effects on causing dizziness, drowsiness and difficulty concentrating.
Zonisamide may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies showing potential risks. The use of Zonisamide is not advisable during pregnancy unless clearly necessary. Please consult your doctor.
Zonisamide is shown to be excreted in human milk and may pose potential risks to breastfed babies. A decision must be made whether to discontinue breastfeeding or discontinue Zonisamide. Please consult your doctor.
There are no studies of Zonisamide on the effect of ability to drive. Do not drive unless you are well.
Dose adjustment is required for patient with kidney impairment. Its usage is not advisable in patients with severe kidney impairment (GFR <50mL/min).
Dose adjustment of Zonisamide is required for patient with liver impairment. Its usage is not advisable in patients with severe liver impairment.