Felodipine

Information About Felodipine

Uses of Felodipine

Felodipine is commonly used in the treatment of hypertension and chronic stable angina pectoris.

How Felodipine Works

Felodipine, a dihydropyridine Ca-channel blocker, produces coronary vasodilation by inhibiting the entry of Ca ions in the myocardium during depolarisation. In addition, it also increases myocardial oxygen delivery

Side Effects of Felodipine

Flushing, Headache, Palpitations, Dizziness, Fatigue, Peripheral oedema, Mild gingival hyperplasia

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Felodipine Related Warnings

Alcohol Not Advisable

Drinking alcohol can aggravate the blood pressure-lowering effect of felodipine. Hypotension can make you feel dizzy or light-headed, all of which could affect your concentration and ability to drive.

Pregnancy Not Safe

Felodipine may be unsafe for use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Lactation Limited Data

Felodipine is probably safe to use during lactation even though it is excreted into breast milk. However, its effect on a feeding baby is largely unknown. Please consult your doctor before using it.

Driving Not advisable

Felodipine may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

Felodipine is well tolerated by patients with concomitant kidney disease. Dose adjustment of Felodipine may be needed. Please consult your doctor before using it.

Liver Limited Data

Felodipine should be used with caution in patients with liver disease because it is metabolized mainly by the liver. Dose adjustment of Felodipine may be needed. Please consult your doctor before using it.