Pirfenidone

Information About Pirfenidone

Uses of Pirfenidone

Pirfenidone is commonly used to treat idiopathic pulmonary fibrosis

How Pirfenidone Works

Pirfenidone is an immunosuppressants and an antifibrotic agent that works by decreasing the amount of inflammatory cells and factors that were found in high amounts in patients with lung fibrosis.

Side Effects of Pirfenidone

Nausea/ vomiting, Diarrhea, Indigestion, Abdominal pain, Weight loss, Dizziness

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Pirfenidone Related Warnings

Alcohol Safe

Although taking Pirfenidone with alcohol may be safe, it is only allowed in very small amount.

Pregnancy Limited Data

Although there is no data available on the effect of Pirfenidone on pregnant women, Pirfenidone should be stopped in planning for a pregnancy or even pregnant mothers.

Lactation Limited Data

It is not known about Pirfenidone effect and excretion in human milk, but animal studies has suggested that the medication is found in the milk.

Driving Not advisable

Do not drive unless you are feeling well. Pirfenidone may cause side effects such as fatigue and dizziness, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Pirfenidone can be used with caution in patients with mild to moderate kidney disease. However, it is contraindicated in patients with severe kidney disease.

Liver Limited Data

Pirfenidone cannot be used in patients with liver problems.