Ticlopidine

Information About Ticlopidine

Uses of Ticlopidine

ticlopidine is commonly used to treat certain condition such as blood clots, and used in the treatment of heart attack, and unstable angina

How Ticlopidine Works

Ticlopidine is an antiplatelet drug that acts by inhibiting platelets from being clumped together in the process best known as platelet aggregation

Side Effects of Ticlopidine

Diarrhea, Nausea, Dyspepsia, Bleeding tendency, Rashes on skin, Increase in serum cholesterol level, Increase of Liver Function Tests

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ticlopidine Related Warnings

Alcohol Not Advisable

Taking alcohol while you are on Ticlopidine may increase the chance of bleeding in your gastrointestinal tract (GIT)

Pregnancy Maybe Safe

Since there are no controlled data in human pregnancy for Ticlopidine and animal studies couldn't demonstrate a risk to the fetus, therefore this medication is advised to be given only when it benefits the pregnant lady

Lactation Limited Data

It is not known whether Ticlopidine is excreted in the breast milk of humans, however, it is excreted in the rat's milk upon research. The decision to continue or stop breastfeeding has to be made by the doctor. Please consult your doctor for further information.

Driving Not advisable

Do not drive unless you are feeling well. Ticlopidine may cause side effects such as dizziness, headches or nausea, all of which could affect the ability to concentrate and drive.

Kidney Use With Care

There is limited study, however, the use of this drug will decrease its plasma clearance and increase bleeding time in a patient with renal impairment. Please consult your doctor before taking this medication.

Liver Limited Data

There is a limited study done for the use of Ticlopidine in patients suffering from the hepatic disease. However, since Ticlopidine is metabolized in the liver, the adjustment of the dosage has to be made by the doctors before initiating the therapy. The use of Ticlopidine is not recommended in patients with severe hepatic disease.