Ampicillin

Information About Ampicillin

Uses of Ampicillin

Ampicillin is commonly used to treat infectious diarrhea, respiratory tract infection, severe bacterial infections

How Ampicillin Works

Ampicillin works by inhibiting the final transpeptidation step of the synthesis of peptidoglycan which forms the bacterial cell wall. This leads to death of the bacteria due to ongoing cell wall disruption enzymatic activity while the cell wall assembly is arrested.

Side Effects of Ampicillin

Nausea, Vomiting, Rashes, Fever, Joint paint, Allergic reaction, Black-hairy mouth, Sore tongue,

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ampicillin Related Warnings

Alcohol Safe

Ampicillin is generally safe to be consumed with alcohol since there is no known interaction nor adverse reaction following consumption of ampicillin and alcohol ever recorded.

Pregnancy Maybe Safe

Animal studies have shown no teratogenic effects and extensive clinical data on pregnant human also suggest the safety of Ampicillin to the women and fetus.

Lactation Limited Data

There is small traces of Ampicillin detected in human breastmilk and limited data suggest that it is compatible to be used during lactation period.

Driving Generally Safe

Ampicillin is not known to affect the ability to drive or operate machinery, thus it is safe to be used before driving.

Kidney Use With Care

Dose adjustment is needed in renal impairment in which dose reduction or increase should be evaluated according to the renal function or whether dialysis is involved or not.

Liver Safe If Prescribed

Ampicillin is safe to be used in hepatic impairment without the need for dosage adjustment as no known adverse effects has been recorded.