Conjugated Estrogens

Information About Conjugated Estrogens

Uses of Conjugated Estrogens

Conjugated estrogens are commonly used to treat vaginal dryness, failure of ovarian development, postmenopausal osteoporosis, prostate cancer, and pain due to menopause. it is also being used as contraception and hormone replacement therapy.

How Conjugated Estrogens Works

Conjugated estrogens comprise of a mixture of synthetic sex hormones. Following menopause, these hormones replace the production of estrogen.

Side Effects of Conjugated Estrogens

Increased risk of breast, endometrial and ovarian cancers, Abdominal pain, Diarrhea, Dyspepsia, Back pain, Edema, Weight gain/loss, Arthralgia, Headache, Breakthrough bleeding, Depression

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Conjugated Estrogens Related Warnings

Alcohol Safe

There is no identifiable risk between consumption of alcohol and conjugated estrogen.

Pregnancy Not Safe - High Risk

It is unsafe to use conjugated estrogens during pregnancy. Both animal and human studies have shown that it may cause fetal abnormalities and the risks to the fetus outweigh the benefits of therapy to mother.

Lactation Not Advisable

It is not safe to use conjugated estrogens during breastfeeding. The presence of estrogens in breast milk may reduce the production of milk.

Driving Generally Safe

Conjugated oestrogen usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

Conjugated estrogens should be used with caution in patients with renal impairment as estrogens may cause fluid retention. Such patients also require close observation.

Liver Use With Care

Conjugated estrogens are contraindicated in patients with acute liver disease or history of liver diseases.