Methylprednisolone

Information About Methylprednisolone

Uses of Methylprednisolone

Methylprednisolone is commonly used to treat arthritis, asthma, cancer, eye disorders, nephrotic syndrome, oral lichen planus, psoriasis, rheumatic disorder, severe allergic reactions, skin disorders

How Methylprednisolone Works

Methylprednisolone works by binding and activating the glucocorticoid receptor which then binds to the promoter region of the DNA resulting in inactivation of genes responsible for inflammatory response.

Side Effects of Methylprednisolone

Impaired healing, Insomnia, Mood swings, Stomach pain, Muscular weakness, Acne, Weight gain, Headache, Vertigo

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Methylprednisolone Related Warnings

Alcohol Safe

There is no clear contraindication on the consumption of alcohol when taking Methylprednisolone.

Pregnancy Limited Data

Methylprednisolone can cross the placenta and may result in abnormality to the fetal development. It should be used in the lowest effective dose and for a short period of time under a specialist supervision.

Lactation Safe If Prescribed

The metabolites of Methylprednisolone been detected in human breastmilk and thus it should be used with caution during breastfeeding only if the benefits outweigh the risks.

Driving Not advisable

It is not advisable to drive when under Methylprednisolone treatment due to its potential side effects such as headache and dizziness which can affect the ability to concentrate and drive.

Kidney Use With Care

Dosage adjustment is not needed but caution should still be exercised for patients with renal impairment.

Liver Safe If Prescribed

There is no dosage adjustment needed for patients with hepatic impairment but caution should be taken if the patient develops signs of hepatotoxicity.