Valsartan

Information About Valsartan

Uses of Valsartan

Valsartan is commonly used in the treatment of heart attack, heart failure, stroke, diabetic kidney disease and also in the prevention of heart attack.

How Valsartan Works

Valsartan is an angiotensin receptor blocker. Valsartan blocks the binding of angiotensin II to angiotensin I receptors, thus antagonising angiotensin I induced vasoconstriction, catecholamine release, aldosterone release, vasopressin release, and water intake.

Side Effects of Valsartan

Hypotension, Discomfort in breathing, Palpitation, Fatigue, Dizziness, Headache, Rash, Diarrhea, Nausea

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Valsartan Related Warnings

Alcohol Not Advisable

It is not advisable to take alcohol with valsartan as it would worsen the adverse reactions such as dizziness, headache, and nausea.

Pregnancy Not Safe

Valsartan is likely to be unsafe to use during pregnancy. Studies have shown positive evidence of human fetal risk. However, in certain conditions, the benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Lactation Limited Data

Limited human data suggests that Valsartan does not represent a significant risk to the baby. It is not recommended during lactation as there are better drugs with established safety efficacy during nursing.

Driving Not advisable

Do not drive unless you are feeling well. Valsartan may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Valsartan should be used with caution in patients with severe kidney disease. Valsartan may affect the efficiency of renal function. In particular conditions such as renal artery stenosis, valsartan is contraindicated to be used. Thus, the dose adjustment of Valsartan may be needed. Please consult your doctor.

Liver Limited Data

Valsartan should be used with caution in patients with liver disease. Dose adjustment of valsartan may be needed for mild and moderate hepatic impairment. Severe liver disease is one of the contraindications for prescription of valsartan. Please consult your doctor.