Patient declaration

What are you taking the medication for?

*Choose one option that best fits your usage (there might be more than 1 correct answer). A pharmacist might contact you if the medication is potentially not suitable for your use

I declare that I am 18 years of age and above. I am fully aware of potential side effects and recommended dosage for the medication that I am purchasing.

IMPORTANT

If you are uncertain or need more assistance about this product, kindly chat with our pharmacist using the on page chat button before purchasing. A pharmacist will be available between 9am-6pm on Mondays - Saturdays

Important Information For Your Reference

Common side effects include: headache, abdominal pain, breast tenderness. For a full list of information
Side Effects:
There could be certain side-effects associated with the usage of the medication. Please refer to the list below:
1. Nausea
2. Vomiting
3. Bloating
4. Abdominal pain
5. Dizziness
6. Headache
7. Migraine
8. Leg cramps
9. Change in libido
10. Mood swings
11. Alopecia
While some these symptoms are more common, there are a few rare symptoms that could also occur. If you are feeling any other symptoms (whether it is mentioned in the above list or not), please consult with a doctor immediately. Please, consult with a doctor if you are having rashes or blurry visions. Report if you experience any other symptoms as the above list may not be exhaustive. These symptoms become more prominent as when one is undergoing a long term therapy with this medication.
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Do not take this if you are allergic to the medicine or its composition. If you're unsure, check with us or your doctor.
Severe allergic reactions such as severe rash, severe itchiness and fever, swollen throat, face, eyelids or lips can happen. Stop taking this medication and speak to your doctor immediately if you experience these symptoms. This reaction may start soon after you first take the medicine, or it might start later.
Other important information for pregnant women/children/elderly users, please

Alcohol Warning (Safe)
There is no identifiable risk between consumption of alcohol and conjugated estrogen.

Pregnancy Warning (Not Safe - High Risk)
It is unsafe to use Premarin 0.625% Vaginal Cream 14g during pregnancy. Both animal and human studies have shown that it may cause fetal abnormalities and the risks to the fetus outweigh the benefits of therapy to mother.

Breastfeeding Warning (Not Advisable)
It is not safe to use Premarin 0.625% Vaginal Cream 14g during breastfeeding. The presence of estrogens in breast milk may reduce the production of milk.

Driving Warning (Generally Safe)
Conjugated oestrogen usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (Use With Care)
Premarin 0.625% Vaginal Cream 14g should be used with caution in patients with renal impairment as estrogens may cause fluid retention. Such patients also require close observation.

Liver Warning (Use With Care)
Premarin 0.625% Vaginal Cream 14g are contraindicated in patients with acute liver disease or history of liver diseases.

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Recommended dosage: Adult: Apply dosage according to your doctors instructions. For external use only and not to be taken. Not recommended for children.

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Product Overview

How To Use Premarin 0.625% Vaginal Cream 14g

Wash your hands thoroughly with soap before and after using the vaginal cream. Fill applicator with the prescribed amount of cream. Lie on your back with knees bent. Gently insert the plastic applicator filled with the cream as deeply and comfortably into the vagina as possible. Gently press down to release the plunger of the applicator until it stops. Remove applicator from vagina. It is recommended that you use this medication at night before you go to bed as a lying position reduces leakage of the product which may occur while sitting or standing. The additional use of a sanitary pad can prevent soiling of your clothing and bedding.

Brands

Pfizer

Active Ingredient

conjugated estrogens

Manufactured by

Pfizer Pharmaceuticals

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

There could be certain side-effects associated with the usage of the medication. Please refer to the list below:

Nausea
Vomiting
Bloating
Abdominal pain
Dizziness
Headache
Migraine
Leg cramps
Change in libido
Mood swings
Alopecia

While some these symptoms are more common, there are a few rare symptoms that could also occur. If you are feeling any other symptoms (whether it is mentioned in the above list or not), please consult with a doctor immediately. Please, consult with a doctor if you are having rashes or blurry visions. Report if you experience any other symptoms as the above list may not be exhaustive. These symptoms become more prominent as when one is undergoing a long term therapy with this medication.

Increased risk of breast, endometrial and ovarian cancers, Abdominal pain, Diarrhea, Dyspepsia, Back pain, Edema, Weight gain/loss, Arthralgia, Headache, Breakthrough bleeding, Depression

Warning Precautions

Precautionary Steps of Premarin 0.625% Vaginal Cream 14g

Please consult a doctor especially before taking Premarin Vaginal Cream. These are the contraindications to the use of Premarin Vaginal Cream:-

Undiagnosed abnormal uterine bleeding
Known or suspected breast cancer
History of thromboembolism or VTE
Liver dysfunction
Pregnancy
Allergy to Premarin Vaginal Cream or any of its components
Hypersensitivity

Please stop using this medication if you are experiencing these symptoms and conditions.

Premarin Vaginal Cream Drug Interactions

Drug to drug interaction reaction of Premarin Vaginal Cream varies from a person to another person. It is advisable to check with your doctor about all the possible drug interactions before starting the medication.

St Johns wort
Phenytoin
Carbamazepine
Rifampicin
Dexamathasone
Cimetidine
Erythromycin
Ketoconazole
Ritonavir

This is an incomprehensive list of drug-to-drug interactions and conditions that might interfere with Premarin Vaginal Cream function. Do inform your doctor about all your current medications prior to consuming this drug.

Keep the following precautions in mind as well:-

Avoid excess exposure to sunlight
Avoid this medicine for a longer use
Tell your doctor if you have any other diseases or if you are taking any other medication
Do not discontinue the prescribed course

Alcohol Warning (Safe)

There is no identifiable risk between consumption of alcohol and conjugated estrogen.

Pregnancy Warning (Not Safe - High Risk)

It is unsafe to use Premarin 0.625% Vaginal Cream 14g during pregnancy. Both animal and human studies have shown that it may cause fetal abnormalities and the risks to the fetus outweigh the benefits of therapy to mother.

Breastfeeding Warning (Not Advisable)

It is not safe to use Premarin 0.625% Vaginal Cream 14g during breastfeeding. The presence of estrogens in breast milk may reduce the production of milk.

Driving Warning (Generally Safe)

Conjugated oestrogen usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (Use With Care)

Premarin 0.625% Vaginal Cream 14g should be used with caution in patients with renal impairment as estrogens may cause fluid retention. Such patients also require close observation.

Liver Warning (Use With Care)

Premarin 0.625% Vaginal Cream 14g are contraindicated in patients with acute liver disease or history of liver diseases.

Quick Tips

Premarin 0.625% Vaginal Cream should be taken according to the recommended dosage and duration.
Apply Premarin 0.625% Vaginal Cream externally or use the applicator provided to insert it into the vagina.
Premarin 0.625% Vaginal Cream avoids side effects that are more common with pills by not exposing the rest of your body to the medicine.
Avoid intercourse after applying Premarin 0.625% Vaginal Cream as it can be exposed to your partner.
Notify your doctor if you have any vaginal bleeding or spotting, abnormal vaginal discharge, or vaginal discomfort while on Premarin 0.625% Vaginal Cream.
Do not administer Premarin 0.625% Vaginal Cream and discuss with your doctor if you're pregnant or breastfeeding, over 35, smoke, or have a history of blood clots or heart disease.